Biomed MDx
In 1957, Jeffries and his colleagues developed a specialized medium to detect the presence of an enzyme called deoxyribonuclease (DNase) produced by certain microorganisms. This enzyme breaks down DNA in the medium. When this medium is flooded with hydrochloric acid, a clear zone appears around colonies of bacteria that produce DNase, indicating the breakdown of DNA. DNase Test Agar has proven valuable in the identification of various bacterial species, including staphylococci, enteric gram-negative bacteria (such as those found in the intestines), and pseudomonads.